Annotation Overview for fig|186497.1.peg.2011 in Pyrococcus furiosus DSM 3638:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1)

current assignment	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1)	EC Number	5.4.2.1
taxonomy id	186497	contig	186497.1:NC_003413 (1,908,257bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
PubMed links	12076796
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPInterProScanRadarPPSearchGram negative CELLOGram positive CELLOProDomPDB
FigFam	FIG118495
data base cross references (dbxref)	NCBI: 20454817 NCBI: 18894161 RefSeq: NP_579688.1 NCBI: 18978331 CMR: NTL01PF1959 UniProt: APGM_PYRFU UniProt: P58814

Annotation History (history of similar genes)

Date	Annotator	Annotation
6/30/2004	last_release	Set FIG function to 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
12/2/2004	guest	Set FIG function to phosphoglycerate mutase [EC:5.4.2.1]
12/2/2004	guest	Set FIG function to phosphonopyruvate decarboxylase bcpc
2/24/2005	SvetaG	Set FIG function to 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1)
3/25/2005	guest	Set FIG function to phosphonopyruvate decarboxylase bcpc
3/28/2005	guest	Set FIG function to 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)
3/28/2005	guest	Set FIG function to phosphoglycerate mutase [EC:5.4.2.1]
8/30/2005	annotation_repair	Annotation for existing assignment 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1) that did not match latest annotation phosphoglycerate mutase [EC:5.4.2.1]
8/30/2005	annotation_repair	Set FIG function to 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1)

We have assigned the function "2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type (EC 5.4.2.1)" to the encoded protein. The protein occurs in 2 subsystems: "Glycolysis and Gluconeogenesis, including Archaeal enzymes", and "Threonine and Homoserine Biosynthesis". In "Glycolysis and Gluconeogenesis, including Archaeal enzymes", it appears to play a functional role that we have not associated with any other gene. In "Threonine and Homoserine Biosynthesis", it appears to play a functional role that we have not associated with any other gene. The function of this gene is asserted in 12076796. The function of genes having the same functional roles have been described in Archaeoglobus fulgidus (17576516) and Methanocaldococcus jannaschii (12062435, 12076796). These are homologous proteins which implement the same function.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.